|Premiere Episode||Reunion, Part 1|
|Premiere Date||September 25, 1999|
|Finale Date||July 1, 2000|
Profiler's fourth and final season premiered on September 25, 1999 on NBC with 23 episodes for season and end it final fourth season on July 1, 2000.
The episode Tsuris which was to be second to last episode of season 4 was pull from being aired and was later aired in July 1, 2000.